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KMID : 0360220220630040352
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Journal of the Korean Ophthalmological Society
2022 Volume.63 No. 4 p.352 ~ p.360
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Clinical Characteristics at Initial Diagnosis of Korean Patients with Retinitis Pigmentosa
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Hwang Jae-Hyeong
Nah Seung-Kwan
Lew Young-Ju
Kim Chul-Gu
Kim Jong-Woo
Kim Jae-Hui
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Abstract
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Purpose: To evaluate the clinical characteristics of Korean patients diagnosed with retinitis pigmentosa.
Methods: We retrospectively reviewed the medical records of patients diagnosed with retinitis pigmentosa from January 2014 to December 2019. We evaluated age, gender, the chief complaints, posterior subcapsular cataract status, abnormalities on optical coherence tomography, visual field test results, and electrooculograms.
Results: A total of 492 eyes of 246 patients were included. The mean patient age was 48.0 ± 16.0 years and the chief complaints were decreased vision and night blindness. The mean logarithm of the minimal angle of resolution (logMAR) best?corrected visual acuity (BCVA) was 0.31 ± 0.50. The BCVA was 0.5 or better in 368 eyes (74.8%). A total of 328 (71.0%) of 462 eyes that underwent visual field testing exhibited visual field defects within 10º. The mean Arden ratio was 1.28 ± 0.28 for the 242 eyes that underwent electro?oculography. Optical coherence tomography revealed vitreomacular traction/an epiretinal membrane, cystoid macular edema, and retinal thinning in 135 (27.4%), 48 (9.8%), and 112 (22.8%) eyes, respectively. The ellipsoid zone was intact in 222 eyes (45.1%), disrupted in 220 (44.7%), and absent in 50 (10.2%).
Conclusions: Most patients with retinitis pigmentosa exhibited visual acuity of 0.5 or better, but also had central visual field defects. Various abnormalities were noted on optical coherence tomography of most patients.
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KEYWORD
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Clinical characteristics, Optical coherence tomography, Retinitis pigmentosa
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